SAMOTHRACE // SiciliAn MicronanOTecH Research And Innovation Center, 2022-2025

As part of the project “SiciliAn MicronanOTecH Research And Innovation Center“, FBK is involved in activities under Spoke 2, focusing on the following key research areas:

• Development of High-Sensitivity Biosensors for Liquid Biopsy

  Research is centered on designing and developing microdevices and biosensors with enhanced sensitivity, specificity, and high-frequency monitoring capabilities. These devices target the detection of molecular markers (e.g., µRNAs, proteins, exosomes) and cellular components (e.g., platelets) in biological fluids. A particular emphasis is placed on the study and integration of fast, efficient sample preparation techniques directly into the sensing platforms.

• 3D Microelectrode Arrays for Neural Activity Mapping

  This line of research focuses on creating 3D devices for mapping electrophysiological activity in organoids and 3D neural tissues. The approach leverages cost-effective post-processing technologies to fabricate vertical 3D microelectrode arrays capable of providing detailed spatial maps of neuron-neuron interactions and neural circuit connectivity.

• Smart Sensing Platforms for Biomedical Diagnostics

  FBK is also developing smart sensing systems that can be embedded in mobile device covers for point-of-care diagnostics. These platforms aim to detect multiple biomedical parameters through blood analysis. A key application is glycemic monitoring in diabetic patients using minimally invasive transdermal sensors.

• Integrated Systems for Environmental Monitoring in Water

  Another research focus is the development of miniaturized sensing systems for detecting microparticles, such as microplastics, in water. These sensors are designed for integration into autonomous, deployable platforms, using advanced microfluidic devices, based on an acoustophoretic principle, to enable real-time, in-situ environmental monitoring.

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The SAMOTHRACE project is funded under the National Recovery and Resilience Plan (PNRR), Mission 4, Component 2, Investment 1.5, funded from the European Union – NextGenerationEU.